1077 matches in the database.
These are records: 1 - 30.
[1] [2] [3] [4] [5] … [36]

1.
Gabel, James M. M.D.
ONE SCIENTIST'S EFFORTS TO PREVENT CHILDHOOD LEAD POISONING.
Degree: MS, Medicine : Environmental Health Sciences, 2001, University of Cincinnati
► Robert A Kehoe, M.D., founder and director of The Kettering Laboratory from…
(more)
▼ Robert A Kehoe, M.D., founder and director of The Kettering Laboratory from 1930 to 1965, urged in 1933 that "strenuous efforts must be devoted to eliminating lead from their [the children's] environment." The history of lead poisoning in the United States can be termed as tragic. Today, we find lead in old buildings and contaminated soil, have passed laws to minimize this hazard, and work to clean up our cities and our industrial sites. Yet, we still have cases of childhood lead poisoning. In 1953, Dr. Kehoe suggested to the Lead Industries Association to implement "a concerted and well organized program of education and control on the part of the paint manufacturers, and distributors, to eliminate the use of paints (and putty) of more than very minor lead content for all inside decoration in the household and in the environment of young children." (32) It was not until 1955 that the American Academy of Pediatrics sponsored the American Standard Association's guideline (American Standard Z66.1-1955) titled "Minimize Hazards to Children from Residual Surface Coating Materials" that industry adopted voluntary guidelines. Meanwhile, Dr. Kehoe continued to inform the public, serve on committees, assist agencies in preventive efforts, and champion legislation at local and national levels. Cincinnati city ordinances were imposed in 1960 for the prevention of childhood lead poisoning, but it was not until 1971 that the federal government passed the first law to reduce the risk of childhood lead poisoning in children. Today, as an outgrowth of Dr. Kehoe's efforts, continuing research and medical activities at the University of Cincinnati contribute to strengthening those efforts in preventing childhood lead poisoning.
Advisors/Committee Members: Donovan, M.D., James R.
Subjects: Environmental Sciences
Keywords: PREVENTION OF CHILDHOOD LEAD POISONING; ENVIRONMENTAL HEALTH; THE KETTERING LABORATORY; ROBERT A. KEHOE
More Like This

2.
GABELMAN, ALAN.
MASS TRANSFER IN DENSE GAS EXTRACTION USING A HOLLOW FIBER MEMBRANE CONTACTOR.
Degree: PhD, Engineering : Chemical Engineering, 2003, University of Cincinnati
► Hollow fiber membrane contactors offer a number of advantages over dispersed phase…
(more)
▼ Hollow fiber membrane contactors offer a number of advantages over dispersed phase contactors for extraction of aqueous feeds. In addition, dense gases provide benefits that traditional extraction solvents do not. A mathematical model of a membrane contactor was developed that predicts the steady state fluid velocities and solute concentrations by solving the applicable conservation equations, with the gravitational force term included. Model predictions were compared to experimental data obtained in our laboratory for the extraction of isopropanol or acetone into dense CO 2 , and to data reported by others for extraction of various solutes into dense CO 2 or propane. Generally, predicted mass transfer coefficients and yields were in reasonable agreement with experimental values, except for data obtained using a module that was particularly susceptible to flow maldistribution and the resulting loss of efficiency. The model predicted that the portion of the mass transfer resistance attributable to the aqueous phase decreased with decreasing solute partition coefficient as expected. Mass transfer coefficients and yields were higher for solutes with higher partition coefficients. A theoretical study of acetone extraction from aqueous solution into supercritical CO 2 was performed, with tube side CO 2 flow with or against gravity. Buoyancy-induced flow was important for large (1.8 mm inside diameter) but not small (0.6 mm ID) fibers, consistent with our expectation that such flow is more difficult to achieve when the characteristic length is small. The importance of buoyancy-induced flow decreased with increasing imposed fluid velocity, as forced convection masked the effects of free convection. For the range of conditions studied, the mass transfer coefficient obtained with flow in the direction of gravity was as much as 33% higher than for flow opposing gravity. Ethanol and isopropanol extractions performed by others using spray, sieve tray or packed columns were run on a simulated membrane contactor, and the resulting values for the height of an equivalent theoretical stage (HETS) were compared to the reported values for the conventional contactors. In most instances the simulated membrane contactor offered a significantly (in some cases, substantially) lower HETS than the corresponding traditional column, indicating that the membrane contactor was more efficient.
Advisors/Committee Members: Hwang, Dr. Sun-Tak.
Subjects: Engineering, Chemical
Keywords: membrane contactor; finite element method; supercritical fluid; dense gas; mass transfer
More Like This

3.
Gabert, Crystal A.
PTSD after traumatic injury: An investigation of the impact of injury severity and peritraumatic and posttraumatic moderators.
Degree: MA, College of Arts and Sciences / Department of Psychology, 2009, Kent State University
► Research has shown that approximately 69% of people have experienced a traumatic…
(more)
▼ Research has shown that approximately 69% of people have experienced a traumatic event in their lifetime and that approximately 7.8% of the general population will develop posttraumatic stress disorder (PTSD) following trauma exposure. Given the debilitating nature of PTSD and the fact that only a small subset of traumatized individuals develop PTSD; it is critical to elucidate variables that aid in the identification of victims who are at high risk of developing PTSD. One variable commonly examined has been injury severity; however, results have been mixed with respect to the impact that injury severity has on risk for PTSD. Methodological differences between studies (i.e. differences in range of injuries examined, measurement of injury severity (subjective or objective), trauma sample, and inclusion of moderating/mediating variables) may account for some of the variability in findings regarding the predictive ability of injury severity for PTSD symptoms. The aim of the present study was to examine subjective and objective injury severity ratings in a heterogeneous sample of trauma victims to determine if these measures would differentially predict PTSD symptoms. Sixty-five adult trauma victims (44 males and 21 females) were assessed within 2-weeks of traumatic injury and then 6-weeks and 3-months post-trauma. Moderation models were conducted to determine whether peri- and posttraumatic factors impacted to the relationship between injury severity and symptom development. Results revealed that subjective injury severity predicted PTSD symptoms at both 6-weeks and 3-months post-trauma. Additionally, for participants appraising their injuries as more severe, the more they dissociated the more PTSD symptoms they reported. Findings indicate that subjective appraisals of the traumatic event should be incorporated into early screeners for PTSD risk and that risk should be determined in light of the moderating impact of peritraumatic dissociation.
Advisors/Committee Members: Delahanty, Douglas.
Subjects: Psychology
Keywords: PTSD; injury severity; moderators
More Like This

4.
Gable, Kristine Marie.
Conodonts and stratigraphy of the Olentangy shale (middle and upper Devonian), central and south-central Ohio.
Degree: Master of Science, Geological Sciences, 1973, Ohio State University
► Ninety-two samples of Olentangy Shale, collected from seven surface sections in central…
(more)
▼ Ninety-two samples of Olentangy Shale, collected from seven surface sections in central and south-central Ohio, yielded 13,480 identifiable conodont elements, which are assigned to the apparatuses of eight Middle and Upper Devonian multielement species. The lower Olentangy Shale contains few diagnostic conodonts, and correlation with either the Tully Formation (upper Givetian) or the Hamilton Group (upper Eifelian to upper Givetian) of New York is plausible. The upper Olentangy Shale lies mainly within the middle Palmatolepis triangularis and the lower crepida zones, is uppermost Frasnian and lower Famennian in age, and is correlatable with part of the Sweetland Creek Shale of Iowa, the Hanover Shale of New York, and the Dunkirk Shale Member of the Perrysburg Formation of New York.
Advisors/Committee Members: Sweet, Walter C.
More Like This

5.
Gabriel, Christopher J.
Effect of localized structural perturbations on dendrimer structure.
Degree: Doctor of Philosophy, Chemistry, 2006, Ohio State University
► The synthesis and conformational properties of folded dendrons based on a 2-methoxyisophthalamide…
(more)
▼ The synthesis and conformational properties of folded dendrons based on a 2-methoxyisophthalamide (2-OMe-IPA) repeat unit are described. The hydrodynamic properties of dendrons preorganized via the syn-syn conformational preference of 2-methoxyisophthalamide are compared with 2,6-pyridinedicarboxamide (2,6-pydic) analogues. The effect of subtle differences in the nature of the conformational equilibria that exist within the 2-OMe-IPA and 2,6-pydic repeat units on the global structural properties of the corresponding dendrons was explored computationally and by 1H-DOSY NMR spectroscopy and time-resolved fluorescence anisotropy (TRFA) measurements. Whereas the syn-syn preference of the 2-OMe-IPA branched repeat unit is stabilized entirely by intramolecular hydrogen-bonding interactions, this preference in the 2,6-pydic system is a consequence of both intramolecular hydrogen-bonding and dipole minimization effects. This branching unit was used to study the effect of placing photoresponsive groups in the interior and throughout compact helical dendrons. Azobenzene was used as the photochemical trigger to induce global conformational changes of the dendritic architecture. 2D-NOESY NMR indicated a highly compact helical structure when the azobenzenes were in the more thermally stable trans-conformation. Photoisomerization of azobenzene from trans to cis, induced a structural change to the compact nature of the dendrons, as evidenced by an increase in the hydrodynamic volume. This change was followed by UV-vis spectroscopy and 1H DOSY NMR. The activation parameters and rate constants of the thermal back isomerization were found.
Advisors/Committee Members: Parquette, Jonathon R.
Subjects: Chemistry, Organic
Keywords: Dendrimer; Azobenzene; Folding; Kinetics; Hydrodynamic Volume
More Like This

6.
Gacura, Matthew David.
Effect of Pleurotus ostreatus on Bioremediation of PAH Contaminated River Sediment.
Degree: Master of Science in Biology, Department of Biological Sciences, 2009, Youngstown State University
► The purpose of this study was to optimize bioremediation of Mahoning River…
(more)
▼ The purpose of this study was to optimize bioremediation of Mahoning River sediment historically contaminated with polycyclic aromatic hydrocarbons (PAHs) using white rot fungi. Pleurotus ostreatus grown on grain (10% v/v) was added to contaminated sediment amended with sawdust (80% v/v), with and without fungal specific nutritional nitrogen (to enhance fungal growth), and with cyclodextrin (to increase PAH availability). Sediment mixtures were incubated in the dark at 25°C for 6 weeks. Sawdust made the sediment more porous, allowed better colonization by fungi, and did not greatly increase volume. Fungal biomass, determined using fluorescent microscopy, indicated initial fungal colonization but then fungal growth was inhibited, likely by toxic metals or high moisture content in the sediment. Growth of unidentified fungi was observed, especially in treatments amended with nitrogen. Total PAH concentrations (in the order of 100 ppm), analyzed using a gas chromatograph mass spectrometer (GCMS), and significantly decreased ~ 50-60% in all treatments, including sediment only controls within the first two weeks. Thus, aerobic degradation by native bacteria and volatilization were likely responsible for most of the observed decreases in PAH concentrations. High heterogeneity of PAHs in this historically contaminated sediment led to high variance between replicates. There was a slight decrease in 5 ring PAHs associated with sediment inoculated with P. ostreatus and also a slight decrease in total PAH concentrations associated with sediment amended with sawdust and cyclodextrin (with or without P. ostreatus). Increased nitrogen did not enhance PAH degradation. Sediment inoculated with P. ostreatus after two weeks, rather than initially, showed better fungal growth and colonization, but PAH data was not yet available. These data indicate there is great potential for bioremediation of PAH contaminated sediment conditions by stimulating indigenous bacteria under aerobic conditions followed by the addition of white rot fungi. However, further testing and optimization is still required.
Advisors/Committee Members: Johnston, Carl.
Subjects: Microbiology
Keywords: Bioremediation; PAHs; White rot fungi; Pleurotus ostreatus; Aerobic degradation; Polycyclic aromatic hydrocarbons
More Like This

7.
Gade, Carmin Jane.
An exploration of the pharmacist-patient communicative relationship.
Degree: Doctor of Philosophy, Communication, 2003, Ohio State University
► The advent of consumerism in healthcare juxtaposed with a massive influx of…
(more)
▼ The advent of consumerism in healthcare juxtaposed with a massive influx of medications available (e.g., prescription, over-the-counter, herbal, alternative therapy), increasing population, decreased number of pharmacists, and the desire to maximize positive health outcomes has resulted in the need to understand the intricacies of the pharmacist-patient communicative relationship. The underlying objectives of this exploratory study included: (1) the determination of current views of pharmacist-patient communication related to traditional medication therapy, as well as increased use of herbal therapies, (2) understanding the perceptions and expectations inherent in the pharmacist’s role as a health care professional, (3) understanding the influence of technology in current pharmacy care and/or the promotion of medication use safety juxtaposed with positive health outcomes; (4) providing recommendations for future research and development in this health care arena. This survey resulted in the identification of three key roles of today’s pharmacists being: 1) traditional role, 2) health care provider role, and 3) alternative therapy source role. A spectrum of pharmacist roles was then developed as both pharmacist and patient respondents agreed to the significance of these roles, in addition to identifying key responsibilities of each participant in this health care relationship. Finally, other key influencers (i.e., medication use safety, technology, herbal/alternative therapies) were shown to be significant considerations. In sum, the results suggest a need to develop communication skills training for pharmacists and patients to assist them in developing shared meaning while realizing positive health outcomes. Much more research is needed, but these results have introduced a framework from which to develop a greater understanding of this communicative relationship.
Advisors/Committee Members: Cegala, Donald J.
Subjects: Speech Communication
Keywords: Pharmacist-Patient communication; Roles; Perceptions; Interpersonal Communication; Alternative Therapies; Safety; Technology
More Like This

8.
Gade, Satya Sai Sravan Kumar.
Preliminary Evaluation Of Post-Production Heat Treating Of HPS 70W Steel.
Degree: MS, Engineering : Civil Engineering, 2008, University of Cincinnati
► The cooperative research program launched by the Federal Highway Administration in cooperation…
(more)
▼ The cooperative research program launched by the Federal Highway Administration in cooperation with the U.S. Navy and the steel industry was a great success in bringing high performance steel technology to the bridge industry. The past decade has seen many developments as part of this research program, the first of them being the development of HPS-70W, a high performance steel material with yield strength of 70 ksi (483 MPa). Its high strength, better weldability, improved toughness, inherent weathering resistance and improved ease of fabrication has helped engineers and bridge owners to design and build bridges more efficiently. Significant material and cost savings have been reported in many of these bridge projects (Wright 1997). HPS-70W is the most widely used, researched and tested of the high performance steels to date. With the success of HPS-70W, an HPS version of 50 ksi (345 MPa) steel has been developed (Wilson 2003). Design specifications for bridges using these steels are being developed and continuously updated as research results are published. Hybrid girder design which incorporates the use of HPS-50W along with HPS-70W has been reported to be effective in using high performance steels for bridge construction. HPS-70W plates up to 4 in (102 mm) thick can be produced by quenching and tempering process (Q&T), but this process limits plate lengths to 50 ft (15 m). A new production technique called Thermal-Mechanical Controlled Processing (TMCP) has recently been developed that yields steel having similar properties (Lwin 2002). TMCP practices can be used to produce HPS-70W plates up to 2 in (51 mm) thick and to 125 ft (38 m) long. The present work concentrates on evaluating various post-production heat treating methods for application to HPS-70W. Methods such as heat curving, heat cambering and flame straightening are used during fabrication and repair of bridge members. There is a concern that these methods might have undesirable effects on the mechanical properties of HPS-70W. The present work focuses on evaluating the effect of these heat treating methods on the properties of HPS-70W, and determining the transition temperature, which is critical during the application of post-production heat treating methods. From the results obtained, it was concluded that post-production heat treating techniques with a limiting temperature of 1275 °F (691 °C) can be used on HPS-70W with no apparent effect on its tensile properties. A more refined approach is required to evaluate the effect on toughness properties of HPS-70W.
Advisors/Committee Members: Swanson, James.
Subjects: Civil engineering
Keywords: Heat Treating; HPS-70W
More Like This

9.
GADE, SRINIVAS.
CHARACTERIZATION OF THE MECHANICAL PROPERTIES OF CARBON NANOTUBE-BASED COMPOSITES USING THE FINITE ELEMENT METHOD.
Degree: MS, Engineering : Mechanical Engineering, 2005, University of Cincinnati
► Carbon nanotubes (CNT) are being used extensively as reinforcing materials at nanoscale…
(more)
▼ Carbon nanotubes (CNT) are being used extensively as reinforcing materials at nanoscale in developing new nanocomposites, because of their excellent mechanical properties. Incorporating CNTs in polymer matrices can potentially enhance the stiffness and strength of composites significantly when compared to those reinforced with conventional carbon fibers. However, retaining these outstanding properties at macro-scale poses a considerable challenge. To discover the ways for achieving this entails extensive experimental and simulation studies. Molecular dynamics (MD) simulations have been proved to be an excellent approach in characterizing nanocomposites. Nevertheless, MD is limited to nanoscale due to its extra-ordinary computational costs, which promoted the development and usage of alternate approaches for characterizing CNT reinforced composites at microscale. In this research one of these alternative approaches, the continuum mechanics approach using the finite element method, is employed to estimate the effective modulus of CNT reinforced composites and was successfully validated using other analytical (rule of mixtures) and MD methods. Large-scale models were developed, simulating CNTs using pipe elements for the first time. Results from these models reveal that there exists a limiting value for the length of long CNT, for effective load transfer. It was also observed that composites reinforced with long CNTs yield very high effective modulus compared to those with short CNTs. These results are found to be in good agreement with those obtained using MD and multi-scale constitutive modeling approaches.
Advisors/Committee Members: Liu, Dr. Yijun.
Subjects: Engineering, Mechanical
Keywords: carbon; nanotube; CNT; SWNT; nanocomposite; polymer; composite; CNT-composite; mechanical properties; FEM; finite element method
More Like This

11.
Gadio, Coumba Mar.
Women's Changing Roles, Issues, and Decisionmaking: The Case of Lebou-Wolof Women Farmers in Thieudeme.
Degree: Doctor of Philosophy, Rural Sociology, 1998, Ohio State University
► Although Senegalese women, like other women in Africa, are central to economic…
(more)
▼ Although Senegalese women, like other women in Africa, are central to economic development and household survival, little has been done to improve working conditions, increase access to resources, and improve productivity. In part this is due to the scarcity of appropriate information on the full range of women's scarcity of appropriate information on the full range of women's roles (household, community, production) and in part to qualitative shortcomings in existing studies. That is, most studies focus on what women produce and how they produce and some even look at cultural constraints to economic roles. However, few studies address the broader, contextual variables and institutional constraints within which women operate; explore continuity and change in women's roles across generations of farmers; examine the linkages between women's roles, levels of production and access to resources, and relative decision making power; or step back from discipline -based concepts and theories to truly listen to women and study them from their own position. That is, few researchers construct variables by analyzing women's reality and by taking into account women's perceptions, concepts and definitions, values, and perspectives. That was the task of this research.The focus is on Lebou-Wolof women farmers in Thiedem, a vegetable producing village in Senegal. Based on findings of an exploratory study carried out in 1993, dissertation research focused on three generations of women and compared the roles, relative power, and perceptions of women who were farmers exclusively with those who farm and market their produce, and of those who participate in self help organizations and those who do not. The general objective was to identify factors that have impacted women's roles, status, and relative decision making power, document how women cope with constraints and responsibilities, and understand women's roles. A survey of 48% of Thieudeme's households provided the study with background information. A sample of 209 women were drawn from these households. The sample was made up of women from three different generations and stratified by socio-economic status. Semi-structured in-depth interviews and life histories were conducted with the sample of women. This comparison of three generations of women farmers' roles in the past and in present day Thieudeme revealed many changes. Changes are taking place in productive and - to a lesser degree - reproductive roles, but also in the ways in which these women farmers are involved and organized in their communities. Changes in productive and reproductive roles can be related to various global, national and local factors such as the changing nature of local and national economies, severe drought, changes in demand for exports and imports, structural adjustment policies, devaluation, local and cultural beliefs.
Advisors/Committee Members: Rakowski, Dr. Cathy A.
More Like This

13.
Gadkari, Sagar A.
A HYBRID RECONFIGURABLE SOLAR AND WIND ENERGY SYSTEM.
Degree: Doctor of Engineering, Fenn College of Engineering, 2008, Cleveland State University
► We study the feasibility of a novel hybrid solar-wind hybrid system that…
(more)
▼ We study the feasibility of a novel hybrid solar-wind hybrid system that shares most of its infrastructure and components. During periods of clear sunny days the system will generate electricity from the sun using a parabolic concentrator. The concentrator is formed by individual mirror elements and focuses the light onto high intensity vertical multi-junction (VMJ) cells. During periods of high wind speeds and at night, the same concentrator setup will be reconfigured to channel the wind into a wind turbine which will be used to harness wind energy. In this study we report on the feasibility of this type of solar/wind hybrid energy system. The key mechanisms; optics, cooling mechanism of VMJ cells and air flow through the system were investigated using simulation tools. The results from these simulations, along with a simple economic analysis giving the levelized cost of energy for such a system are presented. An iterative method of design refinement based on the simulation results was used to work towards a prototype design. T he levelized cost of the system achieved in the economic analysis shows the system to be a good alternative for a grid isolated site and could be used as a standalone system in regions of lower demand. The new approach to solar wind hybrid system reported herein will pave way for newer generation of hybrid systems that share common infrastructure in addition to the storage and distribution of energy.
Advisors/Committee Members: Nayfeh, Taysir.
Subjects: Energy; Engineering; Industrial engineering; Technology
Keywords: hybrid energy system, renewable energy, solar energy, wind energy, levelized cost
More Like This

14.
Gadsden, Cynthia A.
Artforum, Basquiat, and the 1980s.
Degree: Master of Arts (MA), Art History (Fine Arts), 2008, Ohio University
► Jean Michel Basquiat's move from unknown street artist to internationally known gallery…
(more)
▼ Jean Michel Basquiat's move from unknown street artist to internationally known gallery star was solidified with a seminal review in Artforum in late 1981. His distinctive style merged cave-like drawings, the scrawl of the "untrained" artist, and astute observations of culture. His packaging of ethnicity, street background, and artistic style matched seamlessly with Ingrid Sischy's Artforum agenda of art, culture, and race eclecticism. Sischy sought to remodel the magazine to reflect the 1980s fascination with product and image. Basquiat embodied both for Artforum, who shaped his image as an 80s style primitive for 20th century Western art imperialists. Since the early 1960s, Artforum has held the influential position of art world kingmaker. The magazine's primary focus was the traditional art world centered in New York until 1980, when Sischy took the helm of editor. She guided Artforum through a decade of blurring boundaries between money, fine art, and popular culture. Sischy's changes reverberated throughout the art publishing industry. She introduced non-traditional art writers to the magazine, implemented cultural commentary with columns on advertising, television, and music, and added artist projects created specifically for Artforum. The lower East Side of New York was a haven for a different style of artist. Alongside the homeless, prostitutes, and pawnshops grew a subculture of graffiti artists, galleries, and music and dance clubs. A young, African American of Haitian and Puerto Rican descent, Basquiat, was a product of this street culture. Although not a traditional graffiti artist, his early work as part of the duo SAMO tagged walls, buildings, and doors with insightful aphorisms. Though he brought a needed boost to the art market, Basquiat was not inoculated from art world prejudice. In this paper I will contrast the presentation of Basquiat with that of black British artists and filmmakers who directly challenged art racist practices. Through the magazine, Third Text, and film cooperatives like Black Audio Film Collective, they discussed race from the perspective of the non-western Other, something that was lacking in the coverage of Basquiat. The 1980s art market composed of artists, art magazines, gallery owners, dealers, museums, auction houses, and corporate and individual art collectors was not immune to the effects of a culture pre-occupied with money and image. Young, brash business executives saw art as simply an investment vehicle. With thousands rather than millions to spend, auction houses and gallery owners nurtured these new collectors through art education, and appropriated business tactics, such as mortgage style loans and bank financing packages. I selected Artforum because of its influence in the 80s and even today in establishing the career of an artist. Art writing contributes significantly to the success of specific artists, and particular artistic styles and movements. Since the bulk of art writing appears in art journals, these magazines are key in championing particular artists through artist profiles, exhibition reviews, and announcements of upcoming shows. These announcements, or gallery ads, also generate revenue for the magazine. Often artists featured in articles or reviews are the same artists promoted in ads purchased by prestigious galleries, auction houses, and museums, thus illustrating the cyclical, self-serving nature of the art market.
Advisors/Committee Members: Klein, Jeannette.
Subjects: African Americans; Art History; Black history; Economic history; Fine Arts; Journalism
Keywords: Artforum; Jean Michel Basquiat; the 1980s; the art market; art writing; Third Text; Black Audio Film Collective; the lower East Side; Ingrid Sischy; Rene Ricard
More Like This

15.
Gaffey, Kathryn J.
EFFECTS OF WITNESSING INTERPARENTAL VIOLENCE ON YOUNG ADULTS' INTERPERSONAL RELATIONSHIPS.
Degree: Master of Arts, Psychology, 2005, Miami University
► This study examined the impact of witnessing interparental violence (WIV) in childhood,…
(more)
▼ This study examined the impact of witnessing interparental violence (WIV) in childhood, quality of parental care, and witness perceptions of self-blame on the interpersonal relationships and schemas of college students. Approximately 500 male and female students were recruited from undergraduate psychology courses to participate. It was hypothesized that the quality of parental care would moderate the relationship between reports of WIV and maladaptive interpersonal outcomes, such that the quality of parental care would have a larger effect on individuals who had experiences of WIV. The amount of reported self-blame experienced by the offspring was hypothesized to be a mediating factor in this relationship. Self-blame was found to mediate the relationship between WIV and interpersonal distress, as well as between WIV and disrupted interpersonal schemas. Although parental care was not a significant moderator of this relationship, both reported maternal and paternal care were predictors of future interpersonal distress.
Advisors/Committee Members: Messman-Moore, Terri L.
Keywords: interparental violence; interpersonal relationships; domestic violence
More Like This

16.
Gaffey, Kathryn J.
Child Maltreatment Experiences and Romantic Relationship Functioning: The Role of Emotion Dysregulation and Early Maladaptive Schemas.
Degree: Doctor of Philosophy, Psychology, 2009, Miami University
► Child maltreatment has been linked to later romantic relationship difficulties, but the…
(more)
▼ Child maltreatment has been linked to later romantic relationship difficulties, but the mechanisms through which this occurs are unclear. The current study examined a model including two mechanisms, emotion dysregulation and early maladaptive schemas, that were hypothesized to mediate the relationship between cumulative child maltreatment and young adult romantic relationship functioning. It was hypothesized that cumulative child maltreatment would be associated with higher levels of anxiety and avoidance within the context of romantic relationships, and that emotion dysregulation and early maladaptive schemas would account for this relationship. In the current study, 727 college women completed retrospective, anonymous surveys assessing child maltreatment, emotion dysregulation, early maladaptive schemas and attachment-related anxiety and avoidance within romantic relationships. Cumulative maltreatment was a significant predictor of both emotion dysregulation and early maladaptive schemas, which were significant predictors of attachment-related anxiety. Modified models indicated that emotion dysregulation mediated the relationship between child maltreatment and attachment-related anxiety in young-adult romantic relationships. Alternate models including early maladaptive schemas were less parsimonious and had poorer global fit indices. Findings suggest that the incorporation of emotion regulation skills training into interventions with adult survivors of child maltreatment may be integral for decreasing attachment-related anxiety and increasing healthy functioning within romantic relationships.
Advisors/Committee Members: Messman-Moore, Terri.
Subjects: Psychology; Psychotherapy
Keywords: Child Maltreatment, Emotion Dysregulation, Early Maladaptive Schemas, Romantic Relationships
More Like This

17.
Gage, Charles Quincey III.
The meaning and measure of school mindfulness: an exploratory analysis.
Degree: Doctor of Philosophy, Educational Policy and Leadership, 2003, Ohio State University
► The purpose of this inquiry was threefold: first, to conceptualize the construct…
(more)
▼ The purpose of this inquiry was threefold: first, to conceptualize the construct of mindfulness in public schools; second, to operationalize school mindfulness; and third, to develop and test a path model relating mindfulness to faculty trust, enabling school structure, principal disposition toward mindfulness, and collective efficacy. After successfully accomplishing the first two objectives, a path model was advanced to explain the relationships among variables under study. The model proposed direct relations between school mindfulness and collective efficacy, enabling school structure, and principal’s disposition towards mindfulness. Furthermore, it anticipated three positive indirect relations: school mindfulness and faculty trust in the principal, through enabling structure; faculty trust in clients, through collective efficacy; and faculty trust in colleagues, through enabling structure with school mindfulness. The path model was tested with a diverse sample of 75 middle schools in Ohio. The results provided partial support for the model. Significant relationships were found between school mindfulness and both faculty trust in clients and collective efficacy. Further, as anticipated, faculty trust in the principal, enabling school structure and school mindfulness also yielded significant results; however, the paths between the principal’s disposition toward mindfulness and school mindfulness and faculty trust in colleagues and enabling structure were not significant. Finally, the practical, research, and theoretical implications of the findings were discussed. The results of the study were encouraging and are seen as a beginning not an end. A more refined and elaborated model of mindfulness that includes student achievement is the next step in the research agenda. Ultimately, the challenge of designing schools to improve student learning is a paramount objective and school mindfulness seems an important piece of that puzzle.
Advisors/Committee Members: Hoy, Wayne K.
Subjects: Education, Administration
Keywords: Mindfulness, School Mindfulness, Collective Efficacy, Trust, Enabling school structure
More Like This

18.
Gagliano, Wendy Buell.
Biogeochemical characterization of a constructed wetland for acid mine drainage greatment.
Degree: Doctor of Philosophy, Soil Science, 2004, Ohio State University
► Drainage from abandoned coal mines has resulted in severe water quality problems.…
(more)
▼ Drainage from abandoned coal mines has resulted in severe water quality problems. The oxidation of sulfide minerals in coal and associated rocks releases iron-rich, acidic solutions that damage vegetation and aquatic ecosystems. The objective of this study was to characterize the sediment column of an established compost wetland constructed for the treatment of acid mine drainage to gain insight into biogeochemical processes that might impact treatment efficiency. To do this, mineralogy and geochemical stability of ochreous sediments were examined, spatial and seasonal trends in porewater chemistry were measured, and bacterial community composition profiled. The mineralogical composition of the ochre portion of the sediment column was a mixture of schwertmannite [Fe8O8(OH)4.8(SO4)1.6] and goethite (a-FeOOH). Initial drainage conditions favored the precipitation of schwertmannite, which transformed at a rate of 10-30 mol/m3/yr to goethite. The sulfide minerals, pyrite (FeS2) and greigite (Fe3S4), were identified along with magnetite (Fe3O4) in the compost layer of the sediment. Vertical gradients in porewater chemistry were similar throughout the wetland system and, with the exception of dissolved sulfide concentration, no consistent seasonal trends were detected. Dissolved sulfide was elevated in the compost relative to the ochre and in June compared to February. Porewater pH ranged from 3 to 7 and increased with depth; whereas, the Eh ranged from 110 to 750 mV and decreased with depth. Both pH and Eh changed abruptly near the interface between the ochre and compost layers. Dissolved Fe occurred primarily as Fe(II) and peaked within the interface region. Concentrations of other major elements (Al, Ca, K, Mg, Mn, and Na) in the pore waters showed some variation between cells and sampling dates, but vertical gradients generally reflected wetland stratigraphy. Terminal restriction fragment length polymorphism analysis (T-RFLP) of 16S rRNA genes was used to profile bacterial community composition. Bacterial diversity was found to be similar throughout the sediment profile; however, bacterial communities clustered together and could be correlated to sediment properties. Many terminal restriction fragment’s (TRF’s) consistent with bacteria relevant to wetland treatment efficiency were found. These included multiple TRF’s consistent with eight genera of sulfate-reducing bacteria as well as iron-reducers like Shewanella and Peleobacter.
Advisors/Committee Members: Bigham, Jerry M.
More Like This

20.
Gagov, Atanas.
INSTABILITIES IN ELONGATION FLOWS OF POLYMERS AT HIGH DEBORAH NUMBERS.
Degree: Doctor of Philosophy, Polymer Engineering, 2007, University of Akron
► The objective of this work is to study the instabilities of the…
(more)
▼ The objective of this work is to study the instabilities of the contraction flows at high Deborah numbers of various polymers. The following topics will be discussed: 1. Linear and nonlinear stability analysis of isothermal fiber spinning instabilities. 2. Linear stability analysis of nonisothermal fiber spinning instabilities 3. Linear and nonlinear stability analysis of contraction flow instabilities 4. Propagation of reservoir instabilities in capillary The analysis of these flow problems requires solution of the closed set of PDE’s (or ODE’s), consisting of equations for conservation of mass and momentum, along with an adequate viscoelastic constitutive equation, with appropriate initial/boundary conditions. The goal of this work is to demonstrate a procedure for determining the critical regime beyond which the process becomes unstable and also to determine weather the process is stable when the disturbances grow to a finite size. Linear and non-linear stability theories have been used to describe the fluctuations of fiber spinning and contraction flow. Linear stability analysis determines the onset of the instabilities of the process while nonlinear analysis establishes the complete range of the stable and unstable conditions. The melt fiber spinning is the most common of polymer fiber processing. Finding critical process conditions and the stabilizing effect of the cooling is described in this work. The critical draw ratio is established using linear stability analysis and the effect of the finite size imposed disturbances is studied through nonlinear stability analysis. Contraction flow is one of the benchmark problems in computational polymer fluid mechanics and polymer processing. In this modeling, the whole flow region is divided in naturally introduced sub-regions with well-known and highly simplified types of flow. Thus, the model analyzes the entire flow region in a simplified geometric manner with properly matched conditions between adjacent sub-regions. The propagation of the disturbances formed in the reservoir region has been analyzed. Employing the isothermal “Jet approach” followed by linearized perturbation approximation of the governing equations for finding the onset of the instabilities supplies information about the stability of the contraction flow which has been used to describe the mechanism of propagation of the disturbances into capillary up to the die exit, and its numerical implementation.
Advisors/Committee Members: Leonov, Arkadii I.
More Like This

21.
Gahler, Allen M.
The relationship between learning style and selected demographical characteristics of selected Ohio first-year high school agricultural education students.
Degree: Master of Public Health, Agricultural and Extension Education, 2002, Ohio State University
► The purpose of the descriptive, correlational study was to describe the learning…
(more)
▼ The purpose of the descriptive, correlational study was to describe the learning style and selected demographical characteristics of first-year Agricultural Education students enrolled at Bellevue High School, Genoa High School, and Oak Harbor High School. The study further sought to analyze the relationship between the learning style and selected demographical characteristics of the students. The selected demographical characteristics analyzed in the study were age, gender, cumulative grade point average, and residential location, defined as farm or non-farm.The largest groups of first-year Agricultural Education students were male and non-farm residents. The average age of first-year high school Agricultural Education students was 14.73, and their average cumulative grade point average was 2.89. A majority (67.4%) of the first-year high school Agricultural Education students were non-farm residents. The learning style of the first-year high school Agricultural Education students was split almost evenly, with 49.5% (47) of the students exhibiting field dependence, and 50.5% (48) of the students exhibiting field independence.The only significant relationship found between learning style and the selected demographical characteristics was a positive, moderate relationship between learning style and cumulative grade point average. There were no significant relationships between learning style and age, gender, or residential location.
Advisors/Committee Members: Cano, Jamie.
More Like This

22.
GAHL, JESSICA KOHLS.
A THEORY-BASED, DIETARY INTERVENTION FOCUSED ON INCREASING VEGETABLE CONSUMPTION IN POSTPARTUM MOTHERS AND INFANTS.
Degree: MS, Allied Health Sciences : Nutrition, 2007, University of Cincinnati
► Background: Overweight (BMI greater than 25) and obesity (BMI greater than 30)…
(more)
▼ Background: Overweight (BMI greater than 25) and obesity (BMI greater than 30) have reached epidemic proportions in the United States, positioning obesity at the forefront of the nation's health agenda as a critical public health threat. The pregnancy and post-partum periods in women have been identified as stages which may contribute to future obesity. The diets of most Americans are high in calories, fat, and sugar, and low in nutrient dense, low-calorie foods, such as fruits and vegetables. Diets high in vegetables and fruits are linked to reduced risk for chronic disease. Fruit and vegetables are nutrient-dense and low in calories and have recently been associated with reduced risk of major weight gain and obesity development. The purpose of this study was to evaluate the effectiveness of a dietary intervention on increasing vegetable consumption in breast-feeding (BF) and formula feeding (FF) postpartum mothers to aid in attaining a healthy weight. There was no control group in this intervention study as this study was involved in the preparatory stage for a larger study. It was expected that after completion of the program, both groups of mothers would consume more vegetables attributable in part to an increase in vegetable preference and self-efficacy in purchasing, preparing and consuming vegetables. Methods: Postpartum mothers (N=47) were recruited for a dietary intervention with focus on increasing vegetable intake to aid in attaining a healthy weight. The intervention consisted of a pre-evaluation session, nutrition education program, and a post-evaluation session. Results: BF mothers significantly increased their self-efficacy in vegetable selection, preparation and consumption (p=0.01) and FF mothers demonstrated a trend towards increasing self-efficacy (p=0.06). Both groups significantly increased intake of Total Target Vegetables (BF, p= 0.03; FF, p =0.01), Other Vegetables (BF, p= 0.05; FF, p=0.05) and All Vegetables (BF, p=0.01; FF, p=0.01), increasing a total of 1.8 servings for BF and 2.2 servings for FF beyond baseline for all vegetables. Conclusion: A theory-based dietary intervention is effective in increasing vegetable consumption in postpartum women.
Advisors/Committee Members: Falciglia, Dr. Grace A.
Subjects: Health Sciences, Nutrition
Keywords: Postpartum; Vegetable consumption; Weight management; Postpartum weight retention
More Like This

23.
Gaier, Robyn.
Understanding God’s Justice Towards Those Who Suffer: A Critique of Eleonore Stump’s Defense.
Degree: Master of Arts (MA), Philosophy (Arts and Sciences), 2004, Ohio University
► Within philosophical discussions of the problem of evil, the issue of God’s…
(more)
▼ Within philosophical discussions of the problem of evil, the issue of God’s justice towards those who suffer is of primary importance. In this thesis, I consider one aspect of this issue by analyzing and critiquing Eleonore Stump’s claim that justice requires God to compensate the human sufferer for instances of undeserved and involuntary suffering. I critique her view on the grounds that a) such moral constraints upon God exceed what distributive justice requires, b) there is a disparity between her view and its Thomistic foundation, and c) such a view fails to align with the notion of justice advocated in contemporary moral theories.
Advisors/Committee Members: Petrik, James.
Keywords: Philosophy; Religion
More Like This

24.
Gaillard, Trudy R.
Effects of aerobic vs. resistive exercise on glucose transporter proteins and insulin sensitivity in obese nondiabetic female first-degree relatives of African American patients with type 2 diabetes.
Degree: Doctor of Philosophy, Physical Activity and Educational Services, 2005, Ohio State University
► Background: Chronic physical activity has been shown to increase insulin sensitivity (IS)…
(more)
▼ Background: Chronic physical activity has been shown to increase insulin sensitivity (IS) and lower rates of type 2 diabetes (T2DM). There have been no studies that examined the effects of aerobic (AT) and resistive (RT) training in obese, sedentary African Americans (AA) females, who are genetically predisposed to develop T2DM. Thus, the objectives of the present study were; 1) determine the effects of AT vs. RT on glucose transporter proteins (GLUT4) and insulin sensitivity; and 2) examine the impact of genetic inheritance (family history {FH}) on these indices. Methodology: Twenty (20) AA with FH were randomly assigned to 12weeks (12wks) of AT[(70% of VO2max) (n=10)] or RT[(70% of 1 (RM) (n=10)]. Ten(10) AA females without FH served as reference controls [(CN) (n=10)]. OGTT (glucose, insulin, c-peptide), systolic and diastolic blood pressure (SBP, DBP) were obtained in each subject. IS was measured by the Homeostasis Model Assessment (HOMA-IR). Body composition was assessed via BOD POD. Each subject completed a V02max test and 1 repetition maximal (1RM) for chest press(CP) and leg press(LP). Skeletal muscle biopsy for GLUT4 was randomly obtained in a sub-set of each group. Baseline measurements were repeated in subjects with FH after 12wks. Results: The fasting plasma glucose, insulin and c-peptide, HOMA-IR, SBP, DBP, %body fat, were statistically higher in subjects with FH vs. CN. The mean V02max and %lean body mass was statistically lower in our subjects with FH vs. CN. Twelve weeks of AT significantly reduced the SBP and DBP, whereas, RT significant increased body strength. HOMA-IR was not changed by AT or RT. The GLUT4 was not different among our groups. RT was associated with a 24.8% increase in GLUT4 whereas, AT decreased GLUT4 by 10.8% from baseline, but these values were not statistically significant. Summary: Obese AA females with FH of T2DM have greater %body fat, insulin resistance, significantly higher BP and lower V02max when compared to healthy aged-matched AA controls without FH. The two exercise modalities had significant but varying effects on hemodynamic parameters. AT vs. RT had no effects on metabolic or anthropometric parameters measured in our previously sedentary obese AA females.
Advisors/Committee Members: Sherman, William M.
Keywords: Aerobic vs. Resistive Exercise; Insulin Sensitivity; glucose transport; African American females
More Like This

25.
Gailliard, Kristin Michelle.
The Relationship of a Performer’s Visual Communication to Evaluations of Music Performance Quality by Expert and Novice Judges.
Degree: Master of Music (MM), Music Education/Choral Music Education, 2006, Bowling Green State University
► The purpose of this study was to investigate the relationship of a…
(more)
▼ The purpose of this study was to investigate the relationship of a performer’s visual communication (e.g., nonverbal communication, attractiveness, and facial expressions) to evaluators’ judgments of music performance quality. A secondary purpose was to investigate whether characteristics of the evaluators (e.g., expert vs. novice) would influence judgments of performance quality. The music evaluators consisted of music experts and novices drawn from college age students (163 undergraduates and 16 graduates) enrolled in music classes during Fall 2005. Experts were music students (N = 80) majoring in music performance and music education; novices were non-music students (N = 99) majoring in early childhood education. Experts judged technical proficiency to be higher under the casual condition when compared to the formal condition; novices judged technical proficiency to be lower under the casual condition when compared to the formal condition. Novices judged musical understanding more highly than expert judges, regardless of performance condition. The level of music experience of the judges may have affected their evaluations of the formal performance condition and may have created an expectation for higher accuracy in technical proficiency and musical understanding. From this finding, I concluded that music expert judges do take physical attractiveness, performing by memory, and nonverbal and verbal communication into consideration when evaluating performance quality and these are accompanied by higher expectations.
Advisors/Committee Members: Gromko, Joyce.
Subjects: Music
More Like This

26.
Gaines, Kathryn Ann.
A Communicative Theory of Leadership Practice.
Degree: Ph.D., Leadership and Change, 2007, Antioch University
► Addressing three problems in the field of leadership studies - fragmentation across…
(more)
▼ Addressing three problems in the field of leadership studies - fragmentation across disciplines; emphasis on individual leaders in titled positions; failure to identify a coherent set of actions for performing leadership - this study develops a framework of core communicative leadership practices. It is premised on a philosophical analysis of leadership as a social strategy for securing action in service of interests claimed by or for a community - an action performed intentionally via symbolic behavior accessible to any and all members of a community. This definition serves as a heuristic for the development of a systematic theory of leadership practice. The primary guiding question is: How do we participate in leadership? Eight core practices that are fundamental to initiating and participating in leadership are identified and analyzed. The core practices include: reporting and inquiring - to build dialogue and facilitation; directing and pledging - to build commitment and obligation; envisioning and advocating - to inspire and motivate; and declaring and constituting - to create or change social reality. Practices are derived from four functional categories abstracted from the leadership literature, analyzed pragmatically using speech act theory, integrated with multi-disciplinary research, including communication, rhetoric, social psychology, and philosophy, and illustrated through practice-based scenarios. Ultimately, a thoroughly analyzed theory of leadership practice - grounded solidly in the field and integrated with scholarship from other disciplines - is provided with a set of implications and suggestions for the practice, development, and empirical study of leadership.
Advisors/Committee Members: Wergin, Jon F.
Keywords: leadership; theory; communicative practices; speech acts; philosophical analysis; pragmatic analysis
More Like This

27.
Gair, Jonathan Mark.
Evaluating EU-Russian Relations: The Intersection of Variable Geometry and Power Pragmatism.
Degree: Bachelor of Arts, College of Arts and Sciences - Political Science, 2009, Miami University Honors Theses
► Since 1992, both the EU and Russia have seen dynamic changes in…
(more)
▼ Since 1992, both the EU and Russia have seen dynamic changes in their foreign policies with the creation of the Treaty on European Union and the fall of the Soviet Union, respectively. This thesis will be divided into three sections. First, a literature review will take stock of existing research concerning EU, Russian and joint foreign policy actions. Second, an analysis of the relationship will be conducted based on field research, which will explain how the EU follows a difficult path of variable geometry to foreign policy decisions while Russia has embraced a new brand of power pragmatism. The third and final section will bring these different types of foreign policy formations together and present conclusions about the characteristics of the relationship and what future direction we can expect.
Advisors/Committee Members: Mason, Warren.
Subjects: Political science
Keywords: Europe; Russia; NATO; European Union; EU; variable geometry; international relations; CFSP; ESDP; power pragmatism; foreign policy
More Like This

28.
Gaitonde, Suchita S.
RULE-BASED CATEGORY LEARNING: AN EFFECTIVE TREATMENT OPTION IN TRAUMATIC BRAIN INJURY.
Degree: Master of Arts, Speech Pathology and Audiology, 2003, Miami University
► Traumatic Brain Injury (TBI) can cause changes in the physical, emotional, cognitive,…
(more)
▼ Traumatic Brain Injury (TBI) can cause changes in the physical, emotional, cognitive, and psychosocial functioning of the individual. Most of the cognitive rehabilitation programs treating patients with TBI focus on attention and memory retraining. Categorization is one of the most fundamental cognitive processes. Yet research in the area of TBI and categorization is limited. This study investigated one specific aspect, category learning in patients who sustained TBI. The performance of normal subjects was compared to the performance of the TBI subjects on three category-learning tasks. The results of the study indicated that subjects with TBI received more trials and made more errors during spontaneous categorization of stimuli across the 3 levels as compared to the normal subjects. Normal subjects delineated the rules spontaneously more frequently than TBI subjects who required cueing more frequently. In regards to the hierarchical structure of the rules, the number of trials received for spontaneous categorization of stimuli across the 3 levels increased as a function of the steps (1-5) for both the TBI and the normal subjects.
Advisors/Committee Members: Constantinidou, Fofi.
Subjects: Health Sciences, Speech Pathology
Keywords: Categorization; Traumatic Bain Ijury
More Like This

29.
Gaitten, Christopher M.
It Was All in the Interest of Journalistic Science: The Story of Hunter S. Thompson and Gonzo Journalism, 1962-76.
Degree: Master of Science (MS), Journalism (Communication), 2008, Ohio University
► This thesis argued that Hunter S. Thompson's writing style, commonly known as…
(more)
▼ This thesis argued that Hunter S. Thompson's writing style, commonly known as Gonzo journalism, was a style that formed slowly and remained dynamic after its inception. The changes in his writing style were linked with major events in his life, his experiments with drugs and alcohol, and his public persona. This was done through books of his letters, interviews, oral histories, and other published works about his life and writing. The thesis included an in-depth analysis of all of his published articles between 1962 and 1976 and studied how he experimented with his style based on the presence or absence of eight of the main elements of Gonzo journalism.
Advisors/Committee Members: Washburn, Patrick S.
Subjects: Journalism
Keywords: Hunter S. Thompson; Gonzo journalism
More Like This

30.
Gajendrareddy, PraveenKumar.
The role of tissue oxygenation and metalloproteinase expression in stress impaired wound healing.
Degree: Doctor of Philosophy, Oral Biology, 2004, Ohio State University
► Psychological stress impairs healing in humans and animals. Studies suggest stress causes…
(more)
▼ Psychological stress impairs healing in humans and animals. Studies suggest stress causes a decrease in oxygen supply and an increase in oxygen demand in wounds of stressed animals. Hence, we hypothesized that stress dysregulates healing by disrupting oxygen balance, leading to a differential expression of oxygen-sensitive genes. EPR oximetry of the wounds of the stressed animals showed a 17.49 to 34.38 % (p<0.001) reduction in oxygen in these wounds as compared to controls. Expression of iNOS, a hypoxia responsive gene, was elevated in the stressed mice on days 1 (205%; p<0.0003), 3(96%; p<0.04), and 5 (249%; p<0.0003), post-wounding. Measurement of eNOS and nNOS expressions showed a 66% (p< 0.02) increase in the expression of eNOS on day 1 post wounding in the stressed animals as opposed to the controls, while no differences were observed with nNOS expression. Treatment of stressed animals with hyperbaric oxygen therapy (HBO) significantly restored wound healing to near-control levels. HBO treatment also resulted in a significant increase in wound contraction in the stressed animals. HBO treatment decreased iNOS expression in the stressed animals by 89.33% (p< 0.001) on day 1 post-wounding, bringing it to near-control levels. Injection of phentolamine, an alpha-adrenergic antagonist, ameliorated the effect of stress on wound oxygenation on day 1 post-wounding. Subsequently, since psychological stress and oxygen have been shown to differentially regulate gene expression, we hypothesized that psychological stress impaired healing is mediated by altered expression of MMP and TIMP expression. Greater expression of MMP-8 was observed in the stressed groups on days 1 (172%, p<0.0003) and 3 (204%, p<0.0003) post-wounding. The stressed mice showed significantly lower levels of expression of MMP-9 on day-5 post-wounding. On day–5 post-wounding the stressed animals had significantly lower expression of TIMP-1 (56%, p<0.0003). MMP-2 and the constitutively expressed TIMP-2 had no significant differences in expression between the stressed and control animals. Thus, oxygen is seen to play an important role in stress-impaired healing. Impaired wound oxygenation, associated with dysregulated oxygen-sensitive gene expression may be the cause for delayed healing during psychological stress.
Advisors/Committee Members: Marucha, Phillip T.
Subjects: Biology, Molecular
Keywords: Stress; Wound Healing; Oxygen; Hypoxia; Nitric Oxide; Matrix Metalloproteinase
More Like This
[1] [2] [3] [4] [5] … [36]